Novel insight into the distribution of L-cells in the rat intestinal tract
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Novel insight into the distribution of L-cells in the rat intestinal tract. / Hansen, Carl Frederik; Vrang, Niels; Sangild, Per Torp; Jelsing, Jacob.
I: American Journal of Translational Research, Bind 5, Nr. 3, 2013, s. 347-358.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Novel insight into the distribution of L-cells in the rat intestinal tract
AU - Hansen, Carl Frederik
AU - Vrang, Niels
AU - Sangild, Per Torp
AU - Jelsing, Jacob
N1 - CURIS 2013 NEXS 179
PY - 2013
Y1 - 2013
N2 - Gut secreted incretin hormones and gastric bypass surgery currently provides some of the most successful treatments for diabetes and obesity respectively. However, despite the evident importance of the gut endocrine system no information exists on the total number and distribution of different types of endocrine cells in the gut. Here we have used the established preclinical Zucker Diabetic Fatty (ZDF) rat model which displays elevated levels of GLP-1 to assess L-cell distribution and L-cell dynamics in the full rostro-caudal extension of the rat intestinal tract.
AB - Gut secreted incretin hormones and gastric bypass surgery currently provides some of the most successful treatments for diabetes and obesity respectively. However, despite the evident importance of the gut endocrine system no information exists on the total number and distribution of different types of endocrine cells in the gut. Here we have used the established preclinical Zucker Diabetic Fatty (ZDF) rat model which displays elevated levels of GLP-1 to assess L-cell distribution and L-cell dynamics in the full rostro-caudal extension of the rat intestinal tract.
M3 - Journal article
C2 - 23634245
VL - 5
SP - 347
EP - 358
JO - American Journal of Translational Research
JF - American Journal of Translational Research
SN - 1943-8141
IS - 3
ER -
ID: 47522617